RADIOTHERAPY ALTERS EXPRESSION OF MOLECULAR TARGETS IN PROSTATE CANCER IN A FRACTIONATION- AND TIME-DEPENDENT MANNER

Radiotherapy alters expression of molecular targets in prostate cancer in a fractionation- and time-dependent manner

Abstract The efficacy of molecular targeted therapy depends on expression and enzymatic activity of the target molecules.As radiotherapy modulates gene expression and protein phosphorylation dependent on dose and fractionation, we analyzed the long-term effects of irradiation on the post-radiation efficacy of molecular targeted drugs.We irradiated

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Molecular identification and cross immunogenic study on two field isolates of Mycoplasma synoviae isolated from broilers in five districts of Khyber Pakhtunkhwa

Background: Mycoplasma synoviae is an important poultry pathogen causing heavy economic losses Worldwide.Subclinical persistence of this pathogen is the major issue to control its prevalence.Aim: This study aimed to determine the molecular and cross immunogenicity of Mycoplasma synoviae among broiler in five Districts of Khyber Pakhtunkhwa.Methods:

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THE PRIVATISATION AND THE ECONOMICAL ENVIRONMENT OF ARGES COUNTY

The privatisation process has generated over time a lot of controversial opinions of the specialists.The lack of a complete analysis of the privatisation process, Softshell Jackets even now, after more than 20 years from its beginning, has raised questions regarding the accomplishment of the goals of the macro-economic policy.This paper aims to enc

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Engineered Collagen Matrices

Collagen is the most abundant protein in mammals, accounting for approximately one-third of the total protein in the human body.Thus, it is a logical choice for the creation of biomimetic environments, and there is a Full Set long history of using collagen matrices for various tissue engineering applications.However, from a biomaterial perspective,

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